There is no society on Earth that does not in some way celebrate, depend on, profit from, enjoy and also suffer from the use of psychoactive substances … For almost all areas of human activity, there are psychoactive substances that are used with the intention of facilitating that activity in some way … The difference between the enhancement of human performance in some sphere as opposed to its impairment is … a function of the dose taken, the manner of its administration and the setting in which use occurs.
~Stockwell, Gruenewald, Toumbourou & Loxley, 2005, p.4